Dr. Guo is mainly engaged in the pathological diagnosis of breast tumors, and the related research on the invasion and metastasis of breast cancer and tumor microenvironment. Postdoctoral Fellow of Methodist Hospital, Cornell University, USA. Senior Visiting Scholar, National Cancer Center, Tokyo, Japan. Member of the Breast Cancer Professional Committee of the China Anti-Cancer Association, Member of the Standing Committee of the Pathology Committee of the Chinese Women's Physician Association, and member of the Breast Pathology Group of the Breast Cancer Professional Committee of the China Anti-Cancer Association. As the project PI, she has undertaken 3 projects of the National Natural Science Foundation of China (two projects have been completed), as the main participant to participate in the national 863 and 973 projects, the Ministry of Education Breast Cancer innovation team, the National Natural Science Foundation Key projects et al. Published more than 30 SCI paper (including more than 10 articles as first / correspondent author), representative paper published in Clin Cancer Res, Molecular Cell, Modern Pathology et al. As the main accomplisher, she won 7 awards including the first prize of Tianjin Science and Technology Progress Award.